We are happy you chose to try RnBeads! Installing it is very easy. In essence, all you need to do is start an R session and type the following command:
source("http://rnbeads.org/data/install.R")
It executes the installation script we provided on this website that takes care of downloading all dependencies, as well as the RnBeads package itself. For generating reports and plots, please also make sure you have Ghostscript installed on your system. You can find detailed instructions on how to do this here. The complete installation process will typically take 10 to 15 minutes; depending on the number of packages that need to be installed or updated, and on the speed of the computer and Internet connection, the installation may in rare cases take more than one hour to complete. Once the installation script has terminated, you can verify that the installation has been successful by using the following commands:
library(RnBeads)
rnb.run.dj()
We recommend that you use R version 3.1.4 or later with the most recent version of RnBeads.
If you are working with bisulfite sequencing data from the mouse or rat genome or the most recent human genome assembly, you might alsoe need to install the corresponding data packages from bioconductor as listed below, depending on which genome assembly you would like to use. For example, the following command installs the data package for the mouse genome assembly mm10:
install.packages("BiocManager")
library(BiocManager)
BiocManager::install("RnBeads.mm10")